Contaminants never occur in isolation yet legislation is still largely based on effects of single compounds. In addition, more and more data are becoming available that suggest that compounds can exert effects in organisms when present in mixtures in concentration ranges at which the single contaminants do not induce effects. The examination of combined exposures, which corresponds much more realistically to exposure conditions in the environment than the analysis of single substances, entails major methodological difficulties in the experimentation and evaluation procedure. This workshop organised in the context of the European STAR project (Strategy Towards Allied Radioecology) intends to introduce you to some of the approaches and methodologies used in studying and predicting mixture toxicity effects.
The workshop will be a mixture of theoretical presentations and individual practical calculation sessions.